Viruses, lipid rafts and signal transduction
نویسندگان
چکیده
منابع مشابه
[Role of lipid rafts in trimeric G protein-mediated signal transduction].
Lipid rafts and caveolae are microdomains in the cell membranes, which contain cholesterol, glycolipids, and sphingomyelin. While caveolae are relatively stable because caveolin, an integral protein, supports the structure, lipid rafts are considered to be unstable, being dynamically produced and degraded. Recent studies have reported that lipid rafts contain many signaling molecules, such as g...
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Modeling and simulation of signal transduction pathways facilitate the integration of experimental knowledge into a coherent picture and is increasingly regarded as a valuable complement to wet-lab experiments. However, despite its importance, the implications of space (e.g. diffusion, molecular crowding or active transport) have traditionally been neglected in common models of signal transduct...
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Reviews of signal transduction have often focused on the cascades of protein kinases and protein phosphatases and their cytoplasmic substrates that become activated in response to extracellular signals. Lipids, lipid kinases, and lipid phosphatases have not received the same amount of attention as proteins in studies of signal transduction. However, lipids serve a variety of roles in signal tra...
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Eyster KM. The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist. Adv Physiol Educ 31: 5–16, 2007; doi:10.1152/advan. 00088.2006.—Reviews of signal transduction have often focused on the cascades of protein kinases and protein phosphatases and their cytoplasmic substrates that become activated in response to extracellular...
متن کاملNicotinic acetylcholine receptor 7 regulates cAMP signal within lipid rafts
Jin Oshikawa,1 Yoshiyuki Toya,1 Takayuki Fujita,1 Masato Egawa,2 Junichi Kawabe,3 Satoshi Umemura,1 and Yoshihiro Ishikawa1,3 1Departments of Physiology and Medicine, Yokohama City University School of Medicine, and 2Department of Medical Pathophysiology, Yokohama City University College of Nursing, Yokohama 236-0004, Japan; and 3Cardiovascular Research Institute, Departments of Medicine and Ce...
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ژورنال
عنوان ژورنال: Signal Transduction
سال: 2007
ISSN: 1615-4053,1615-4061
DOI: 10.1002/sita.200600113